Showing posts with label badger vaccine. Show all posts
Showing posts with label badger vaccine. Show all posts

Thursday, October 13, 2011

First UK badger vaccination trial results published

Vaccinating badgers against bovine tuberculosis (bTB) is an affordable and viable alternative to culling according to a new report published today, by Gloucestershire Wildlife Trust.

The Badger Vaccination Deployment Programme, which took place this summer, was the first of its kind in the UK undertaken by a private organisation. Gloucestershire Wildlife Trust ran the programme at seven of its nature reserves, including a dairy farm; an area totalling 170 hectares.
The report outlines the full costs involved in the trial and demonstrates that if groups of land owners join together to vaccinate badgers against bTB, it would become affordable with no associated negative impact. Culling, as its most vocal supporters admit, may increase bTB in neighbouring herds through perturbation and as yet no proven benefit.

“We are delighted with the results. The report provides proof that there is an affordable alternative to the proposed cull” Said Dr. Gordon McGlone OBE, Chief Executive of Gloucestershire Wildlife Trust.

“Bovine TB is a big problem but local culling of one of our much-loved native animals is not the answer. Scientists have spent that last 12 years investigating whether killing badgers will halt this serious disease in cattle and the answer they are getting is that it could well make the problem worse.”

The report suggest ways in which badger vaccination could be made cheaper, such as the removal of the Certificate of Competence costs and also recommends a free bTB vaccine advisory service is set up.

Costing only £51 per hectare, The Trust wants the Government and landowners to take badger vaccination seriously as a viable alternative to the proposed cull.

For press enquiries call Emma Bradshaw on 01452 383333 (9-3 Mon- Thurs) or mobile 07740 922193.

Notes…
Gloucestershire Wildlife Trust is a county-wide charity which manages 60 nature reserves covering over 2,000 acres, in addition to identifying key sites of nature importance. Its aim is to secure a natural environment which the people of Gloucestershire and visitors to the area can enjoy for generations to come. It has a local membership of more than 25,000 people and works with 450 regular volunteers who give their time to support the Trust’s work. Further information can be found at www.gloucestershirewildlifetrust.co.uk.
http://www.wildlifetrusts.org/news/2011/10/12/first-uk-badger-vaccination-trial-results-published

Wednesday, April 20, 2011

Badger vaccine pilot planned by National Trust in Devon

20 April 2011
By Richard Black
Environment correspondent, BBC News

The National Trust is to vaccinate badgers against TB this summer in a bid to curb the disease in cattle - the first UK landowner to do so.

The trust hopes its £320,000, four-year project on Devon's Killerton estate will make the case for vaccination as an alternative to culling.

Cattle (or bovine) tuberculosis costs the UK about £100m each year.

The government is set to approve badger culling in England soon, and the Welsh Assembly Government also plans a cull.

Research published last year showed the vaccine lowers infection in badgers.

Some cattle herds contract TB through contact with badgers, which carry the bacterium, although infection from other cattle is more significant.

Badger culling is a controversial option and although the trust is not opposed to it in principle, it is troubled by research showing it could do more harm than good - hence the vaccination scheme.

"This is a pilot project - it's not research, not a trial - we know the vaccine works, and we're going for it," said David Bullock, the trust's head of nature conservation.

"The driver is that we want to reduce the risk of bovine TB breakdowns in cattle herds belonging to our tenant farmers, 18 of whom are involved in this project - and we also want to see that the vaccine is considered nationwide."

Last December, scientists with the government-owned Food and Environment Research Agency (Fera) published the results of a four-year field trial using an injectable TB vaccine.

It showed that vaccination reduced the incidence of TB in badgers by 74%, but did not look for any impact on infection levels in cattle.

The Labour government had planned five subsequent pilot vaccination projects, but the coalition reduced that to one, and Killerton was among the sites axed.

So at a cost of £80,000 per year, the National Trust is picking up the project, making use of the fact that some of the preliminary research (such as mapping out badger setts) has already been done.

Across about 20 sq km (8 sq miles) of the site, badgers will be lured into cages with bait and trapped.

Trained and licensed Fera staff will then deliver a dose of vaccine and release the badger, first marking it so it does not subsequently receive a second shot.

Dozens of setts have been identified, and the trust believes many hundreds of badgers will be vaccinated.

Promises made

The Conservative Party made badger culling a plank of their general election campaign last year.

The National Farmers' Union (NFU) has demanded it for a long time and after the election Agriculture Minister Jim Paice - a farmer himself - announced a public consultation into how it should be implemented in England.

While supporting the trust's decision to carry out the pilot programme, the NFU said vaccines formed part of the long-term solution but did not address the "desperate plight" that many farmers currently found themselves in.

"Current vaccination methods of injecting badgers is costly, and practically challenging with the benefits remaining unclear, and unproven," Melanie Hall, the NFU's regional director for South-West England told BBC News.

"As the vaccine is preventative, [it is] unlikely to impact positively on infected badgers."

Nationwide, nearly 35,000 cattle were slaughtered last year and there is no vaccine yet that can be used in cattle.

The government believes a cull would reduce disease incidence in cattle by 16% over nine years.

A spokesman for the Department of Environment, Food and Rural Affair (Defra) welcomed the National Trust's plans to run a vaccine pilot project.

He added: "There's no one solution to tackling TB, and the badger vaccine we developed is one of the tools we have available.

"We will be announcing a comprehensive and balanced TB Eradication Programme for England as soon as possible."

Ministers were expected to publish their plans to deal with bovine TB in the national herd in February; but amid turmoil over the disposal of nationally-owned forests, the announcement was postponed, and is now expected next month.

Meanwhile, the Welsh Assembly Government has announced new plans for a pilot cull in Pembrokeshire this year, after a legal ruling derailed similar plans last year.

Animal rights campaigners are to challenge the new plans in the courts.

Scientific cloud

Behind the issue lie conflicting interpretations of scientific evidence on the effectiveness of culling.

The Westminster and Cardiff governments and the NFU argue that culling can markedly reduce bovine TB incidence in cattle.

But the major UK investigation, the Randomised Badger Culling Trial (also called the Krebs trial), showed culling only produced a benefit if conducted rigorously and systematically over large areas, ideally with hard boundaries that badgers could not cross.

Otherwise, the social structure of badger groups broke down when some were killed, and the animals ranged further afield - infecting more cattle and leading to increased TB incidence.

"We're not against culling badgers if it's going to be effective in curbing bovine TB, but you can't apply the criteria everywhere that would make it effective," Mr Bullock told BBC News.

"Unless you have boundaries, you may have this effect where badgers move around and spread TB - we know from the science that this does happen."

Scientists who ran the Krebs trial have warned the government that its plan to allow shooting of badgers as they roam was likely to be less effective than the trap-and-shoot method deployed during the trial.

On that basis, they said, culling "risks increasing rather than reducing the incidence of cattle TB".

In the Irish Republic, culling has been practised for many years and does appear to have curbed bovine TB; but scientists involved with that programme say the disease will not be eradicated without vaccination.

The National Trust argues that vaccination could prove to be a more effective option than culling, in conjunction with tightened regulations designed to prevent cattle-to-cattle transmission.

This would also, of course, avoid killing badgers, which are a protected species under UK and EU laws.

Eventually, the aim is to have an oral vaccine that badgers would simply eat, avoiding any need for trapping; but that is thought to be five years away.

http://www.bbc.co.uk/news/science-environment-13121520
(Via Dawn Holloway)

Saturday, December 4, 2010

Badger vaccine partial success – But culling still recommended

Badger vaccine and culling

December 2010. Control of bovine tuberculosis (TB) in cattle has proven particularly challenging where reservoirs of infection exist in wildlife populations. In Britain and Ireland, control is hampered by a reservoir of infection in Eurasian badgers.

Badger culling
Badger culling has positive and negative effects on bovine TB in cattle and is difficult, costly and controversial. A new study, published in the Royal Society's scientific journal Proceedings, shows that Bacillus Calmette-Guérin (BCG) vaccination of captive badgers reduced the progression, severity and excretion of Mycobacterium bovis infection after experimental challenge.

Reduced infection levels
In a clinical field study, BCG vaccination of free-living badgers reduced the incidence of positive serological test results by 73.8 per cent. In common with other species, BCG did not appear to prevent infection of badgers subjected to experimental challenge, but did significantly reduce the overall disease burden. BCG vaccination of badgers could comprise an important component of a comprehensive programme of measures to control bovine TB in cattle.

First badger vaccine licensed
Defra has made public supporting data behind the successful licensing of the first tuberculosis vaccine for badgers (Badger BCG), which was licensed by the Veterinary Medicines Directorate. The studies were carried out by the Veterinary Laboratories Agency (VLA) and the Food and Environment Research Agency (Fera).

74% reduction in infection
A key finding of the field study, conducted over four years in a naturally infected population of more than 800 wild badgers in Gloucestershire, was that vaccination resulted in a 74 per cent reduction in the proportion of wild badgers testing positive to the antibody blood test for TB in badgers.

The blood test is not an absolute indicator of protection from disease, so the field results cannot tell us the degree of vaccine efficacy. While the findings indicate a clear effect of vaccination on badger disease, data from the laboratory and field studies do not lend themselves to giving a definitive figure for BadgerBCG vaccine efficacy. Nor do they provide information on the effect of badger vaccination in reducing TB incidence in cattle.


Professor Glyn Hewinson, Head of the TB Research Group at the VLA, and Professor Robbie McDonald, Head of the Wildlife and Emerging Diseases Programme at Fera, said: "VLA and Fera are very proud to have conducted the programme of work on BadgerBCG and that a vaccine is now available for use in the field as one of the tools for tackling bovine TB. In making the data available today, we hope that people will be able to see for themselves the detailed research that went into the development of the vaccine and understand the opportunities and challenges of using vaccination."

Positive result?
Defra has also published the results of new computer modelling by the Food and Environment Research Agency (Fera), which has examined different strategies for controlling TB in badgers, including both culling and vaccination.

The results of the modelling were consistent with the conclusions of the Randomised Badger Culling Trial indicating that there were both positive and negative effects of culling. The modelling shows that badger vaccination could make a positive contribution to disease control in its own right and was consistently positive when used in combination with culling in a ring vaccination strategy. Wildlife Extra questions what measure has been used for ‘positive'? Has this been taken measured from the point of view of farmers or wildlife?

The results of the modelling were:

A combined strategy of vaccination in a ring around a culling area was more successful than the cull-only strategy, which in turn was more successful than the vaccination-only strategy, both in reducing the number of TB infected badgers and cattle herd breakdowns. Ring vaccination partly mitigated the detrimental effects of culling. However, the combined strategy requires about twice as much effort than either single approach done in isolation

Culling of badgers should continue for at least four years to realise a clear benefit. However, low rates of land access for culling, or low culling efficiency, or the early cessation of a culling strategy was likely to lead to an overall increase in cattle herd breakdowns (whilst this is not the case for vaccination).

http://www.wildlifeextra.com/go/news/badger-vaccine.html

Badger vaccine partial success – But culling still recommended

Badger vaccine and culling

December 2010. Control of bovine tuberculosis (TB) in cattle has proven particularly challenging where reservoirs of infection exist in wildlife populations. In Britain and Ireland, control is hampered by a reservoir of infection in Eurasian badgers.

Badger culling
Badger culling has positive and negative effects on bovine TB in cattle and is difficult, costly and controversial. A new study, published in the Royal Society's scientific journal Proceedings, shows that Bacillus Calmette-Guérin (BCG) vaccination of captive badgers reduced the progression, severity and excretion of Mycobacterium bovis infection after experimental challenge.

Reduced infection levels
In a clinical field study, BCG vaccination of free-living badgers reduced the incidence of positive serological test results by 73.8 per cent. In common with other species, BCG did not appear to prevent infection of badgers subjected to experimental challenge, but did significantly reduce the overall disease burden. BCG vaccination of badgers could comprise an important component of a comprehensive programme of measures to control bovine TB in cattle.

First badger vaccine licensed
Defra has made public supporting data behind the successful licensing of the first tuberculosis vaccine for badgers (Badger BCG), which was licensed by the Veterinary Medicines Directorate. The studies were carried out by the Veterinary Laboratories Agency (VLA) and the Food and Environment Research Agency (Fera).

74% reduction in infection
A key finding of the field study, conducted over four years in a naturally infected population of more than 800 wild badgers in Gloucestershire, was that vaccination resulted in a 74 per cent reduction in the proportion of wild badgers testing positive to the antibody blood test for TB in badgers.

The blood test is not an absolute indicator of protection from disease, so the field results cannot tell us the degree of vaccine efficacy. While the findings indicate a clear effect of vaccination on badger disease, data from the laboratory and field studies do not lend themselves to giving a definitive figure for BadgerBCG vaccine efficacy. Nor do they provide information on the effect of badger vaccination in reducing TB incidence in cattle.


Professor Glyn Hewinson, Head of the TB Research Group at the VLA, and Professor Robbie McDonald, Head of the Wildlife and Emerging Diseases Programme at Fera, said: "VLA and Fera are very proud to have conducted the programme of work on BadgerBCG and that a vaccine is now available for use in the field as one of the tools for tackling bovine TB. In making the data available today, we hope that people will be able to see for themselves the detailed research that went into the development of the vaccine and understand the opportunities and challenges of using vaccination."

Positive result?
Defra has also published the results of new computer modelling by the Food and Environment Research Agency (Fera), which has examined different strategies for controlling TB in badgers, including both culling and vaccination.

The results of the modelling were consistent with the conclusions of the Randomised Badger Culling Trial indicating that there were both positive and negative effects of culling. The modelling shows that badger vaccination could make a positive contribution to disease control in its own right and was consistently positive when used in combination with culling in a ring vaccination strategy. Wildlife Extra questions what measure has been used for ‘positive'? Has this been taken measured from the point of view of farmers or wildlife?

The results of the modelling were:

A combined strategy of vaccination in a ring around a culling area was more successful than the cull-only strategy, which in turn was more successful than the vaccination-only strategy, both in reducing the number of TB infected badgers and cattle herd breakdowns. Ring vaccination partly mitigated the detrimental effects of culling. However, the combined strategy requires about twice as much effort than either single approach done in isolation

Culling of badgers should continue for at least four years to realise a clear benefit. However, low rates of land access for culling, or low culling efficiency, or the early cessation of a culling strategy was likely to lead to an overall increase in cattle herd breakdowns (whilst this is not the case for vaccination).

http://www.wildlifeextra.com/go/news/badger-vaccine.html